Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies

Chillo, Serawit Lakew; Woldesemayat, Endrias Markos; Dangisso, Mesay Hailu

doi:10.1186/s12978-024-01917-8

Reproductive Health

Table 2 Summarized basic characteristics of included studies, July 2023

From: Intermittent versus daily oral iron folic acid supplementation and pregnancy outcome in low- and middle-income countries: a systematic review and meta-analysis of experimental studies

Authors, year published	Study design	Country	Gestation at recruitment (weeks)	Gestation at outcome measurement (weeks)	Frequency of supplementation in the week	Iron dose (weekly/daily) (in mg)	Sample size
Abdelgawad M. et al. 2021	RCT	Egypt	13–20	25–32	Once weekly	200/100	125
Yaznil M.R. et al. 2020	RCT	Indonesia	13–28	26–40	Twice-weekly	120/60	62
Ekstrom E-C. et al. 2002	RCT	Bangladesh	14–22	26–34	Once weekly	120/60	140
Bhatla N. et al. 2009	RCT	India	14–18	30–34	Once weekly	200/100	60
Hanieh S. et al. 2013	RCT	Vietnam	< 16	32	Twice-weekly	120/60	705
Rajoria L. et al. (a), 2018	RCT	India	14–16	34	Thrice-weekly	180/60	57
Rajoria L. et al. (b), 2018	RCT	India	14–16	34	Once weekly	60/60	66
Goshtasebi A. et al. 2012	Quasi-RCT	Iran	14–20	37–40	Twice-weekly	100/50	360
Mukhopadhyay A. et al. 2004	RCT	India	14–20	32–34	Once weekly	200/100	80
Hyder SM. et al. 2002	RCT	Bangladesh	18–24	22–28	Once weekly	120/60	172
Sipra B. et al. 2015	RCT	India	16–22	28–34	Once weekly	200/100	89
Ridwan E. et al. 1996	RCT	Indonesia	8–24	28–32	Once weekly	120/60	139
Young et al. 2000	RCT	Malawi	≤ 30	36	Once weekly	120/60	216
Grover V. et al. 1998	RCT	India	16–24	37–40	Alternate day	400/100	120
Saxena R. et al. 2017	RCT	India	14–20	18–24	Once weekly	200/100	200
Utari D.M. et al. 2017	RCT	Indonesia	≤ 27	≤ 35	Once weekly	60/60	104
Haque N. et al. 2010	RCT	Bangladesh	18–22	28	Once weekly	120/120	57
Mumtaz Z. et al. 2000	RCT	Pakistan	20–22	32–34	Twice-weekly	120/60	105
Robinson. et al. 1999	RCT	Indonesia	No report	No report	Once weekly	120/60	399
Musa G. et al. 2021	RCT	Nigeria	16–24	30–38	Twice-weekly	130/65	120
Chitra TV. et al. 2020	RCT	India	10–14	32–34	Alternate day	400/100	173
Gomber S. et al. 2002	RCT	India	16–24	30–38	Once weekly	100/100	56

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