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Table 4 Association between biomarkers concentrations and blood pressure with pre—pregnancy body mass index (pBMI) in 178 pregnant women

From: Effects of pre-pregnancy body mass index on cardiometabolic biomarkers in pregnant emirati women

 

Univariate modela

Multivariate modelb

Response variable

Coefficient (95% ci)

p − value

Coefficient (95% ci)

p − value

Interaction between pBMI and trimester of pregnancy (p-value)

Systolic BP (mmHg)

 − 1.23 (− 2.68, 0.21)

0.093

0.047 (− 0.14, 0.24)

0.626

NA

Diastolic BP (mmHg)

0.75 (− 0.10, 1.61)

0.085

 − 0.003 (− 0.13, 0.13)

0.965

NA

HbA1C (%)

0.050 (− 0.02, 012)

0.184

NA

NA

NA

RBG (mmol/L)

0.006 (− 0.081, 0.21)

0.379

NA

NA

NA

GGT (IU/L)

 − 0.56 (− 1.67, 0.55)

0.320

NA

NA

0.05

Total − C (mmol/L)

 − 0.02 (− 0.20, 0.16)

0.848

NA

NA

NA

HDL (mmol/L)

0.039 (− 0.03, 0.11)

0.283

NA

NA

NA

LDL (mmol/L)

 − 0.05 (− 0.24, 0.14)

0.608

NA

NA

NA

TG (mmol/L)

 − 0.07 (− 0.21, 0.78)

0.351

NA

NA

NA

LP − a (nmol/L)

0.175 (− 10.86, 11.21)

0.975

NA

NA

NA

APO − A (g/L)

0.017 (− 0.050, 0.08)

0.621

NA

NA

NA

APO − B (g/L)

 − 0.021 (− 0.08, 0.04)

0.507

NA

NA

NA

Hs − CRP (mg/l)

 − 0.031 (− 0.96, 0.89)

0.947

NA

NA

NA

IL − 6 (pg/ml)

 − 0.098 (− 0.41, 0.22)

0.542

NA

NA

NA

TNF − α (pg/ml)

 − 0.09 (− 0.53, 0.33)

0.656

NA

NA

NA

IGF − 1 (ng/ml)

 − 5.69 (− 15.47, 4.07)

0.252

NA

NA

NA

sICAM − 1 (ng/ml)

 − 4.00 (− 14.77, 6.76)

0.464

NA

NA

0.008

sVCAM − 1 (ng/ml)

0.966 (− 20.09, 22.26)

0.867

NA

NA

NA

Systolic BP (mmHg)

 − 1.23 (− 2.68, 0.21)

0.093

0.047 (− 0.14, 0.24)

0.626

NA

Diastolic BP (mmHg)

0.75 (− 0.10, 1.61)

0.085

 − 0.003 (− 0.13, 0.13)

0.965

NA

  1. ci: confidence intervals; BP: blood pressure; HbA1c: hemoglobin A1c; RBG: Random blood glucose; GGT: gamma-glutamyl transferase; Total-C: total cholesterol; HDL: high-density lipoprotein; LDL: low-density lipoprotein; TG: triglycerides; Lp-a: lipoprotein-a; Apo-A: apolipoprotein-A; Apo-B: apolipoprotein-B; Hs-CRP: high-sensitivity C-reactive protein; IL-6: interleukin-6; TNF-α: tumor necrosis factor-alpha; IGF-1: Insulin-like growth factor-1; sICAM-1: soluble intercellular cytoadhesive molecule-1; sVCAM-1: soluble vascular cytoadhesive molecule-1; NA: not applicable
  2. aLinear regression model
  3. blinear regression adjusting for maternal age, trimester of pregnancy, education level, and parity