Table 5 Association between blood pressure and biomarkers concentrations with trimester of pregnancy in 178 pregnant women
From: Effects of pre-pregnancy body mass index on cardiometabolic biomarkers in pregnant emirati women
Response variable | Univariate modela | Multivariate modelb | Interaction between pBMI and trimester of pregnancy | ||
|---|---|---|---|---|---|
Coefficient (95% ci) | p-value | Coefficient (95% ci) | p-value | p-value | |
Systolic BP (mmHg) | − 1.23 (− 2.68, 0.208) | 0.093 | − 1.08 (− 2.74, 0.58) | 0.21 | NA |
Diastolic BP (mmHg) | − 1.00 (− 2.00, − 0.006) | 0.049 | − 1.11 (− 2.27, 0.053) | 0.061 | NA |
HbA1C (%) | − 0.05 (− 0.27, 0.14) | 0.184 | NA | NA | NA |
RBG (mmol/L) | − 0.024 (− 0.19, 0.14) | 0.779 | NA | NA | NA |
GGT (IU/L) | − 2.06 (− 3.31, − 0.81) | 0.001 | − 1.67 (− 2.96, − 0.38) | 0.011 | 0.05 |
Total-C (mmol/L) | 0.87 (0.70, 1.04) |  < 0.001 | 0.97 (0.78, 1.16) |  < 0.001 | NA |
HDL (mmol/L) | 0.15 (− 0.07, 0.23) |  < 0.001 | 0.18 (0.09, 0.27) |  < 0.001 | NA |
LDL (mmol/L) | 0.92 (0.75, 1.09) |  < 0.001 | 1.03 (0.84, 1.22) |  < 0.001 | NA |
TG (mmol/L) | 0.59 (0.42, 0.76) |  < 0.001 | 0.59 (0.42, 0.76) |  < 0.001 | NA |
LP-a (nmol/L) | − 5.04 (− 17.7, 7.68) | 0.435 | NA | NA | NA |
APO-A (g/L) | 0.23 (0.16, 0.30) |  < 0.001 | 0.23 (0.16, 0.31) |  < 0.001 | NA |
APO-B (g/L) | 0.32 (0.26, 0.37) |  < 0.001 | 0.35 (0.29, 0.41) |  < 0.001 | NA |
Hs-CRP (mg/l) | − 0.03 (− 0.96, 0.89) | 0.947 | NA | NA | NA |
IL-6 (pg/ml) | − 0.44 (− 0.80, − 0.08) | 0.016 | − 0.49 (− 0.88, − 0.092) | 0.016 | NA |
TNF-α (pg/ml) | − 0.68 (− 1.18, − 0.19) | 0.007 | − 0.77 (− 1.31, − 0.22) | 0.006 | NA |
IGF-1 (ng/ml) | 15.90 (4.82, 26.99) | 0.005 | 15.39 (2.91, 27.87) | 0.016 | NA |
sICAM-1 (ng/ml) | 2.24 (− 10.20, 14.70) | 0.722 | NA | NA | 0.008 |
sVCAM-1 (ng/ml) | − 2.06 (− 26.38, 22.26) | 0.867 | NA | NA | NA |